13th Meeting

of the

European Epidermal Barrier Research Network

(E2BRN)


9-10 September 2015

Rotterdam (The Netherlands)

Scientific Organising Committee:
Sandrine Dubrac (Innsbruck, Austria) and Patrick Zeeuwen (Nijmegen, The Netherlands)


Email addresses:
sandrine.dubrac@i-med.ac.at
Patrick.Zeeuwen@Radboudumc.nl


Website: E2BRN



Final program of the E2BRN meeting - pdf (70 kb) last update: August, 7th, 2015

 

Scientific Program

Wednesday, September 9, 2015

13:00 - 14:40

Session 1
(Topic – skin barrier: mechanisms of disease)

Chairs: Johanna Brandner (Hamburg) & Patrick Zeeuwen (Nijmegen)
Keynote lectures: 20 min + 5 min discussion each

13:00 - 13:05
Opening E2BRN meeting by Johanna Brandner

13:05 - 13:30
Keynote lecture 1
Stephan Weidinger (Kiel, Germany)
Barrier and Bases

13:30 - 13:55

Keynote lecture 2
Johanna Brandner (Hamburg, Germany)
Interaction of the tight junction barrier and the stratum corneum barrier


3 Short communications chosen from the abstracts
(12 min + 3 min discussion each)

13:55 - 14:10

Laura Ivanovas (Gießen, Germany)
Inflammation and stress: The epidermal tight junctions under attack

14:10 - 14:25

Reiko Tanaka (London, UK)
In silico models to study the onset, progression and prevention of AD

14:25 - 14:40

Alexander Boreham (Berlin, Germany)
Skin penetration and tumor specific cellular uptake of G5G2.5 tecto-dendrimer nanoparticles as a new strategy for targeted delivery by topical application


 
14:40 - 16:00

Coffee break + poster session

 
16:00 - 17:35

Session 2
(Topic – Organotypic 3D cultures: models to study atopic dermatitis)

Chairs:
Sandrine Dubrac (Innsbruck) & Katja Bäsler, Hamburg
Keynote lectures: 20 min + 5 min discussion each

16:00 - 16:25
Keynote lecture 3
Dusco Ilic (London, UK)
Gene editing of human pluripotent stem cells in modeling atopic dermatitis in vitro
16:25 - 16:50
Keynote lecture 4
Gitta Neufang (Hamburg, Germany)
Innervated skin models: Implication for atopic dermatitis

3 Short communications chosen from the abstracts
(12 min + 3 min discussion each)

16:50 - 17:05
Evelyne De Vuyst (Namur, Belgium)
Cholesterol-depletion followed by interleukins-4, -13 and –25 enhances alterations in a reconstructed human epidermis

17:05 - 17:20
Jeroen van Smeden (Leiden, The Netherlands)
Altered Epidermal Lipid Biosynthesis in Patients with Atopic Dermatitis

17:20 - 17:35
Li Fang Koh (Singapore)
TAp63β and Notch in human skin differentiation

 
17:35 - 17:45
Poster Prizes
 
 
Thursday, September 10, 2015

08:30 - 10:30 Session 3
(Topic – Skin barrier homeostasis)

Chairs:
Michel Simon (Toulouse) & Stefan Blunder (Innsbruck)
Keynote lectures: 20 min + 5 min discussion each

08:30 - 08:55
Keynote lecture 5
Howard Maibach (San Francisco, USA)
BARRIERS: Lessons Learned

08:55 - 09:20
Keynote lecture 6
Matthias Schmuth (Innsbruck, Austria)
Epidermal permeability barrier: Lessons from monogenetic disease

09:20 - 09:45
Keynote lecture 7
Ellen van den Bogaard (Nijmegen, The Netherlands)
The aryl hydrocarbon receptor (AHR) in skin barrier homeostasis and disease

3 Short communications chosen from the abstracts
(12 min + 3 min discussion each)

09:45 - 10:00
Aurelie Hayez (Namur, Belgium)
TMEM45A gene expression is dispensable for epidermal keratinization and morphogenesis

10:00 - 10:15
Emmi Wachsmut (Cologne, Germany)
p38 Map kinase compensates barrier dysfunction caused by loss of epidermal insulin/IGF-1 signaling

10:15 - 10:30
Matthias Schäfer (Zurich, Switzerland)
A novel Nrf2-Il-36γ pathway mediates paracrine growth control of keratinocytes