European Epidermal Barrier Research Network

European Epidermal Barrier Research Network

European Epidermal Barrier Research Network

European Epidermal Barrier Research Network

Research Focus

  1. Involvement of Tight Junctions in barrier function of epidermis and hair follicles

  2. Extrinsic and intrinsic influences on (epidermal) wound healing

  3. Establishment of ex vivo and in vitro skin models for wound healing, infection, barrier research and drug testing




Publications Prof. Dr. J. Brandner

Link to PubMed

Publications not listed in PubMed:

  1. Gruber R, Elias PM, Crumrine D, Lin TK, Brandner JM, Hachem JP, Presland RB, Fleckman P, Janecke AR, Sandilands A, McLean WH, Fritsch PO, Mildner M, Tschachler E, Schmuth M
    Filaggrin genotype in ichthyosis vulgaris predicts abnormalities in epidermal structure and function
    Am J Pathol, 178(5):2252-63, 2011

  2. Kirschner N, Haftek M, Niessen CM, Behne MJ, Furuse M, Moll I, Brandner JM CD44 Regulates Tight-Junction Assembly and Barrier Function J Invest Dermatol, 131(4):932-43, 2011

  3. Gruber R, Elias PM, Crumrine D, Lin TK, Brandner JM, Hachem JP, Presland RB, Fleckman P, Janecke AR, Sandilands A, McLean WH, Fritsch PO, Mildner M, Tschachler E, Schmuth M Filaggrin genotype in ichthyosis vulgaris predicts abnormalities in epidermal structure and function Am J Pathol, 178(5):2252-63, 2011

  4. Kirschner N, Houdek P, Fromm M, Moll I, Brandner JM Tight Junctions form a barrier in human epidermis Eur J Cell Biol, 89:839-42, 2010

  5. Peters EMJ, Liezmann C, Spatz K, Daniltchenko M, Joachim R, Gimenez-Riveral A, Hendrix S, Botchkarev V, Brandner JM, Klapp BF Dissecting the role of nerve growth factor in allergic inflammation: Nerve growth factor partially recovers inflamed skin from stress-induced worsening J Invest Dermatol, 131(3):735-43, 2011

  6. Werling AM, Doerflinger Y, Brandner JM, Fuchs F, Becker JC, Schrama D, Kurzen H, Goerdt S, Peitsch WK Homo- and heterotypic cell-cell contacts in Merkel cells and Merkel cell carcinomas: surprising heterogeneity and indications for cadherin switching Histopathol, 58(2):286-303, 2011

  7. Pollok S, Pfeiffer A-C, Lobmann R, Wright CS, Moll I, Martin PEM, Brandner JM Connexin 43 mimetic peptide Gap27 reveals potential differences in the role of Cx43 in wound repair between diabetic and non-diabetic cells Cell Mol Med, 15(4):861-73

  8. Haass NK*, Ripperger D*, Wladykowski E, Dawson P, Gimotty PA, Blome C, Fischer F, Schmage P, Moll I, Brandner JM Melanoma progression exhibits a significant impact on connexin expression patterns in the epidermal tumor microenvironment Histochem Cell Biol 133:113-24, 2010. 2009 Oct 21. *shared first-authorship

  9. Vockel M, Breitenbach U, Kreienkamp H-J, Brandner JM Somatostatin regulates tight junction function and composition in human keratinocytes Exp Dermatol, Exp Dermatol, 19:888-94, 2010

  10. Kirschner N, Poetzl C, von den Driesch P, Wladykowski E, Moll I, Behne MJ, Brandner JM Alteration of tight junction proteins is an early event in psoriasis: Putative involvement of proinflammatory cytokines Am J Pathol, 175:1095-106, 2009

  11. Liew CW*, Vockel M*, Glassmeier G, Brandner JM, Fernandez-Ballester GJ, Schwarz JR, Schulz S, Buck F, Serrano L, Richter D, Kreienkamp HJ Interaction of the human somatostatin receptor 3 with the multiple PDZ domain protein MUPP1 enables somatostatin to control permeability of epithelial tight junctions FEBS Lett. 583:49-54, 2009

  12. Eispert AC, Fuchs F, Brandner JM, Houdek P, Wladykowski E, Moll I Evidence for distinct populations of human Merkel cells Histochem Cell Biol 132:83-93, 2009

  13. Fischer N*, Brandner JM*, Fuchs F, Moll I, Grundhoff A Detection of Merkel cell polyomavirus (MCPyV) in Merkel cell carcinoma cell lines: cell morphology and growth phenotype do not reflect presence of the virus Int J Cancer 126:2133-2142, 2010. Sept 08 *shared first-authorship

  14. Rickelt S, Franke WW, Doerflinger Y, Goerdt S, Brandner JM, Peitsch WK Subtypes of melanocytes and melanoma cells distinguished by their intercellular contacts: heterotypic adherens junctions, adhesive associations, and dispersed Desmoglein 2 glycoproteins Cell Tissue Res, 334:401-422, 2008

  15. Ohnemus U, Willers C, Bubenheim M, Hostkotte, MA, Houdek P, Fischer F, Schmage, P, Moll I, Brandner JM An ex-vivo oral mucosa infection model for the evaluation of the topical activity of antifungal agents Mycoses, 51:21-29, 2008

  16. Ohnemus U, Kohrmeyer K, Houdek P, Rohde H, Wladykwoski E, Vidal S, Horstkotte MA, Aepfelbacher M, Kirschner N, Behne MJ, Moll I, Brandner JM Regulation of epidermal Tight Junctions (TJ) during infection with exfoliative toxin-negative Staphylococcus strains J Invest Dermatol, 128:906-916, 2008

  17. Brandner JM, Zacheja, S, Houdek P, Moll I, Lobmann R Expression of matrix metalloproteinases, cytokines and connexins in diabetic and non-diabetic human keratinocytes before and after transplantation into an ex-vivo wound healing model Diabetes Care, 31:114-120

  18. Neub A, Houdek P, Ohnemus U, Moll I, Brandner JM Biphasic regulation of AP-1 subunits during human epidermal wound healing J Invest Dermatol 127:2453-2462, 2007

  19. Brandner JM, Kief S, Wladykowski E, Houdek P, Moll I Tight junction proteins in the skin Skin Pharmacol Physiol 19:71-77, 2006

  20. Haass NK, Wladykowski E, Kief S, Moll I and Brandner JM Differential induction of connexins 26 and 30 in skin tumors and their adjacent epidermis J Histochem Cytochem 54:171-182, 2006

  21. Brandner JM, Houdek P, Hüsing B, Kaiser C and Moll I Connexins 26, 30 and 43: Differences between spontaneous, chronic and accelerated human wound healing J. Invest. Dermatol. 122:1310-1320, 2004

  22. Meyer CG, Amedofu GK, Brandner JM, Pohland D, Timmann C and Horstmann RD Selection for deafness? Nat. med. 8:1332-1333, 2002

last update: May 2018