European Epidermal Barrier Research Network

European Epidermal Barrier Research Network

European Epidermal Barrier Research Network

European Epidermal Barrier Research Network

Research Focus

  1. Percutaneous absorption of hazardous materials through normal and damaged skin

  2. Treatment after percutaneous challenge with hazardous materials

  3. Intra and transdermal drug delivery

  4. Non invasive measurement



Research Focus Picture


Important Publications

  1. Payne, O.J., Graham, S.J., Dalton, C.H., Spencer, P.M., Mansson, R., Jenner, J., Azeke, J., Braue, E.
    “The effects of sulphur mustard exposure and freezing on transdermal penetration of tritiated water through ex vivo pig skin”
    Toxicology in vitro 27: 79-83 (2013)

  2. Hattersley, I. J., Jenner, J., Dalton, C.H., Chilcott, R. P., and Graham, J. S.
    “The skin reservoir of sulphur mustard”
    Toxicology in Vitro 22 1539-1546 (2008)

  3. Chilcott, R.P., Dalton, C.H., Ashley, Z., Allen, C.E., Bradley, S.T., Maidment, M.P., Jenner, J., Brown, R.F.R., Gwyther, R.J. and Rice, P.
    “Evaluation of barrier creams against sulphur mustard: (II) in vivo and in vitro studies using the domestic white pig”
    Cutaneous and Ocular Toxicology 26 (3): 235-247 (2007)

  4. Dalton, C.H., Hattersley, I.J., Rutter, S.J. and Chilcott, R.P.
    “Absorption of the Nerve Agent VX (O-ethyl-S-[2(diisopropylamino)ethyl] methyl phosphonothioate) through pig, human and guinea pig skin in vitro”
    Toxicology in vitro, 20: 1532-1536 (2006)

  5. Dalton, C.H., Maidment M.P., Jenner J. and Chilcott, R.P.,
    “Closed cup vapour systems in percutaneous exposure studies: What is the dose?”
    Journal Analytical Toxicology 30 (3): 165 - 170 (2006)

  6. Chilcott, R.P., Dalton, C.H., Emanuel, A.J., Allen, C. and Bradley, S.,
    “Transepidermal water loss (TEWL) does not correlate with skin barrier function in vitro”.
    Journal of Investigative Dermatology 118(5) 871 – 875 (2002)

  7. Dalton, C.H. and Chilcott, R.P.
    “Exposure to UVB Radiation Does not Directly Impair Skin Barrier Function”.
    Toxicology 168 pp136 (2001)

last update: 2013, February