European Epidermal Barrier Research Network

European Epidermal Barrier Research Network

European Epidermal Barrier Research Network

European Epidermal Barrier Research Network

Research Focus

  1. Percutaneous absorption through normal and compromised skin

  2. Skin barrier in atopic eczema

  3. Individual susceptibility to irritant contact dermatitis



Research Focus Picture


Important Publications

  1. Kezic S, Kemperman PM, Koster ES, de Jongh CM, Thio HB, Campbell LE, Irvine AD, McLean WH, Puppels GJ, Caspers PJ. Loss-of-function mutations in the filaggrin gene lead to reduced level of natural moisturizing factor in the stratum corneum. J Invest Dermatol. 2008 Aug;128(8):2117-9

  2. de Jongh CM, Khrenova L, Verberk MM, Calkoen F, van Dijk FJ, Voss H, John SM, Kezic S. Loss-of-function polymorphisms in the filaggrin gene are associated with an increased susceptibility to chronic irritant contact dermatitis: a case-control study. Br J Dermatol. 2008 Sep;159(3):621-7

  3. Jakasa I, Verberk MM, Esposito M, Bos JD, Kezic S. Altered penetration of polyethylene glycols into uninvolved skin of atopic dermatitis patients. J Invest Dermatol. 2007 Jan;127(1):129-34

  4. Jakasa I, Verberk MM, Bunge AL, Kruse J, Kezic S. Increased permeability for polyethylene glycols through skin compromised by sodium lauryl sulphate. Exp Dermatol. 2006 Oct;15(10):801-7

  5. Jakasa I, de Jongh CM, Verberk MM, Bos JD, Kezi? S. Percutaneous penetration of sodium lauryl sulphate is increased in uninvolved skin of patients with atopic dermatitis compared with control subjects. Br J Dermatol. 2006 Jul;155(1):104-9

  6. de Jongh CM, Jakasa I, Verberk MM, Kezic S. Variation in barrier impairment and inflammation of human skin as determined by sodium lauryl sulphate penetration rate. Br J Dermatol. 2006 Apr;154(4):651-7

last update: 2009, May