European Epidermal Barrier Research Network

European Epidermal Barrier Research Network

European Epidermal Barrier Research Network

European Epidermal Barrier Research Network

Research Focus

  1. Regulation of genes networks involved in epidermal homeostasis

  2. Non-coding RNAs and skin aging

  3. Epidermal response to environmental stresses



Research Focus Picture


Important Publications

  1. Barbollat-Boutrand L, Joly-Tonetti N, Dos Santos M, Metral E, Boher A, Masse I, Berthier-Vergnes O, Bertolino P, Damour O, Lamartine J.
    microRNA-23b-3p regulates human keratinocyte differentiation through repression of TGIF1 and activation of the TGF-ß -SMAD2 signaling pathway
    Exp Dermatol. 2017 jan ;26(1) :51-57

  2. Barbollat-Boutrand L, Thepot A, Muther C, Boher A, Robic J, Guéré C, Vié K, Damour O, Lamartine J.
    Repeated short climatic change affects the epidermal differentiation program and leads to matrix remodeling in a human organotypic skin model
    Clin Cosm Invest Dermatol 2017 Feb 13, 10-43-50.

  3. Barbollat-Boutrand L, Joly-Tonetti N, Dos Santos M, Metral E, Boher A, Masse I, Berthier-Vergnes O, Bertolino P, Damour O, Lamartine J.
    microRNA-23b-3p regulates human keratinocyte differentiation through repression of TGIF1 and activation of the TGF-ß -SMAD2 signaling pathway
    Exp Dermatol. 2017 jan ;26(1) :51-57

  4. Masse I, Barbollat-Boutrand L, El Kharbili M, Berthier-Vergnes O, Joly-Tonetti N, Aubert D, Lamartine J.
    GATA3 inhibits proliferation and induces expression of both early and late differentiation markers in keratinocytes of the human epidermis
    Arch Dermatol Research 2014; 306(2) : 201-218.

  5. Joly-Tonetti N, Vinuelas J, Gandrillon O, Lamartine J.
    Differential miRNA response in proliferating or differentiated keratinocytes in response to gamma irradiation
    BMC Genomics. 2013; 16;14(1):184.

  6. Masse I., Barbollat-Boutrand L, Molina M, Berthier-Vergnes O, Joly-Tonetti N, Martin MT, Caron de Fromentel L, Kanitakis J, Lamartine J.
    Functional interplay between p63 and p53 controls RUNX1 function in the transition from proliferation to differentiation of human keratinocytes
    Cell Death Dis. 2012; 7;3:e318

  7. Wu N, Rollin J, Masse I, Lamartine J, Gidrol X.
    p63 regulates human keratinocyte proliferation via a MYC-regulated gene network and differentiation commitment through a cell adhesion-related network
    J Biol Chem. 2012; 287(8):5627-38

  8. Bonin F, Molina M, Malet C, Ginestet C, Berthier O, Martin M, Lamartine J.
    GATA3 is a master regulator of the transcriptional response to low-dose ionizing radiation
    BMC Genomics 2009, 10:417

  9. Vigano MA, Lamartine J, Testoni B, Merico D, Alotto D, Castagnoli C, Robert A, Candi E, Melino G, Gidrol X, Mantovani R. ( 2006)
    New p63 targets in keratinocytes identified by a genome-wide approach
    EMBO J. Nov 1;25(21):5105-16

  10. Franco N, Lamartine J, Frouin V, Le Minter P, Petat C, Leplat JJ, Libert F, Gidrol X, Martin MT. (2005)
    Low-dose exposure to gamma rays induces specific gene regulations in normal human keratinocytes
    Radiat Res. Jun;163(6):623-35.

  11. Lamartine J, Franco N, Le Minter P, Soularue P, Alibert O, Leplat JJ, Gidrol X, Waksman G, Martin MT. (2005)
    Activation of an energy providing response in human keratinocytes after gamma irradiation
    J Cell Biochem. Jun 1;95(3):620-31.

  12. Baghdoyan S, Lamartine J, Castel D, Pitaval A, Roupioz Y, Franco N, Duarte M, Martin MT, Gidrol X. (2005)
    Id2 reverses cell cycle arrest induced by {gamma}-irradiation in human HaCaT keratinocytes
    J Biol Chem. Apr 22;280(16):15836-41

  13. Lamartine J, Munhoz Essenfelder G, Kibar Z, Lanneluc I, Callouet E, Laoudj D,Lemaitre G, Hand C, Hayflick SJ, Zonana J, Antonarakis S, Radhakrishna U, Kelsell DP, Christianson AL, Pitaval A, Der Kaloustian V, Fraser C, Blanchet-Bardon C, Rouleau GA, Waksman G.
    Mutations in GJB6 cause hidrotic ectodermal dysplasia
    Nature Genetics. 2000 Oct;26(2):142-144.

last update: 2017, July