European Epidermal Barrier Research Network

European Epidermal Barrier Research Network

European Epidermal Barrier Research Network

European Epidermal Barrier Research Network

Research Focus

  1. Cellular differentiation programs that regulate the formation and homeostasis of the epidermis

  2. The role of proteases and protease inhibitors in epidermal differentiation and desquamation

  3. Skin barrier formation and cutaneous host defense mechanisms

  4. Skin microbiome research (in normal situation and in the setting of the pathogenesis of AD and psoriasis)

  5. 3D skin models and microbiome: search for pre-, pro-, and anti-biotics



e2brn - Research Focus Picture
Recolonization after stripping. The tree-like structure in the left side of the figure is the consensus tree. The pie charts shows the microbial community composition of the individual samples in time (t1-t14 days). Composition is displayed as relative abundance, i.e. the number of reads assigned to a genus divided by the total number of reads assigned up to the genus level. STR0 is non-damaged healthy superficial skin and STR10 represent 10 times tape-stripped skin.

Figure from Zeeuwen et al. Genome Biology 2012 Nov 15;13(11):R101



last update: 2018, October